HCG, “Questionable” Studies, The Placebo Effect And More…
As recently witnessed by Elissa in this superb post, things are really heating up on the HCG feedback page over at Real-Customer-Comments.com (if you’re interested in learning about HCG and the Simeons protocol, you can read the full review of HCG here!)
Seems I’ve really irked a few folks by pointing out that ALL the documented evidence shows that HCG does not provide any benefit over that provided by a placebo. While these folks may have experienced great results on the protocol, it’s likely they are directly attributable to the Very Low Calorie Diet (VLCD) and not the effects of HCG.
In gently replying to one individual who insisted otherwise, I stated…
“That does not mean that new, larger scale studies on HCG will show different, more beneficial results. And we’ll be happy to revise our conclusion on HCG… but only when we have some peer-reviewed data to base that revision on. But until then, we have to rely on the only evidence we have.”
Within a day of posting that, one individual quoted this material back to me and commented…
“You have to rely on the only evidence you have? Have you read all the comments on your website? Did you notice that 99% are positive? You bash HCG in your article and almost every post has had success with HCG. Who are you to say that it doesn’t work to these people that experienced it first hand?
Have you considered doing your own tests? Or will you continue to be ignorant and except tests that should clearly be questioned?”
Uh-huh.
Let’s address this comment, starting with most obvious point…
1) Personal commentary is always anecdotal. That does not mean its worthless, of course. To draw from Elissa’s earlier post which referenced cancer surgeon/researcher/skeptic/med-blogger ORAC…
“In science- and evidence-based medicine, anecdotes are indeed the raw material from which we as medical scientists derive hypotheses, and “anecdotes” are published all the time in the medical literature. They’re called “case reports.” We do not dismiss them out of hand just because they are “anecdotes.” When appropriate, we dismiss “anecdotes” because frequently they are “testimonials” and not controlled observations or because anecdotes themselves, even when the observations are controlled, are often deceiving, which is why further study in the form of more controlled trials is always necessary before science-based medicine will accept a claim. Anecdotes are not enough…”
And to reiterate; HCG is administered along with a Very Low Calorie Diet. And VLCDs do work. Anyone on the Simeons / HCG protocol will likely lose weight; and not necessarily because of the HCG injections. In fact, that’s exactly what the published data indicates; that HCG does not provide any benefits above that of a placebo.
2) Can a dozen or so positive comments be considered representative of a diet protocol that was developed back in the 50’s, and has had thousands, perhaps even hundreds of thousands of participants? Even if these comments were not anecdotal, how could such a small number constitute real evidence, exactly?
3) The placebo effect is very real.
To address some of the specific comments directly…
4) We are not “bashing” HCG. To what motive, exactly? That’s not what we do here. Our job is to look at the existing data, compare it to the claims, and report on the results.That’s it, that’s all. All the published data is clear: HCG does not provide any benefit over a placebo. Simple. Period. If we were to provide a contrary position, what evidence would we base that on? Tarot cards? An augury?
5) “Tests that should clearly be questioned”: Questioned why, exactly? Because they don’t conform to your specific set of beliefs? Or do you have some inside knowledge into some violation of a critical testing protocol in one of the clinical studies? As Elissa said in her post, “small and old don’t add up to ‘wrong’”. And even so, a more recent meta-analysis verified these studies with its own identical conclusion.
6) Maybe should consider doing your own tests: Why should we? It’s not our job. The onus is on those selling the HCG protocol to demonstrate to their customers that it works. After all, they are the ones making the money. And even if we did conduct such a study, why would you accept it? After all, you’re quick to dismiss all the published data I’ve already referenced.
Now I do recognize it may be hard to accept that something you are paying a lot of money for is not based on sound science. But unless you want to hand over your wallet and credit cards to anyone who makes you a promise of any sort, it’s best not to take complete leave of your senses and attack anyone who delivers a contrary message.
Especially when all he is doing is reporting on the facts and has no financial incentive to do otherwise.





Elissa on 15 May 2009 at 1:05 am #
As they also say: “the plural of anecdote is NOT data.”
fat guy on 15 May 2009 at 4:33 am #
elissa should do more steroids her face isnt there yet
Elissa on 15 May 2009 at 6:00 am #
Nor will it ever be, I’m afraid, as I don’t do steroids – never have.
Your point?
Paul on 15 May 2009 at 2:30 pm #
Fat Guy, it’s a good thing Elissa approved your comment first – I would have just deleted it. I’m simply not interested in having this blog degrade to this level.
I’m not sure if you’re trying to be funny, or if this is your response to an argument you cannot present a valid countering opinion to.
Whatever it is, good for you for hiding behind an anonymous moniker and e-mail address. What courage you’ve shown! What insight! What wit!
BTW, unless you have something meaningful to add to the conversation, your next “post” will be deleted.
Elissa on 15 May 2009 at 9:13 pm #
LOL Paul: I approved it ’cause that s**t makes me laugh.
But back to hCG: first of all, nice post!
I don’t know what – if anything – you’ve added to the commentary at Real-Customer-Comments.com, but it might be worth referring some of the protesters to my follow-up comment here as well, to reinforce how we look at these sorts of things here.
Stephanie on 10 Jun 2009 at 1:21 am #
Hi,
I am early in my HCG journey. I have so far found great results, as have many other people who I have talked to.
I have tried MANY other weight loss programs, and none of them worked.
Now I know that the studies say that the placebo works just as well as the HCG. My response to that? So what? I am losing weight & getting healthier! If it is a placebo effect, or if it really helps, I don’t care! I am getting results.
I also know that there are clinics out there charging outrageous prices for this. I am lucky! I live in a small town, no big weight loss clinics around here. My Dr prescribed the HCG for me and that is all I have to pay for.
I know my response doesn’t change any of the studies or some peoples opinions, but I’m a believer.
Editor’s comments: What the placebo effect means in this case is that the HCG protocol (i.e., a very low calorie diet and intensive support from supervising technicians) works just as well with or without the HCG. In other words, it’s the diet coupled with the support that works, and the HCG makes no difference.
Cindy on 10 Jun 2009 at 3:47 am #
I was on hcg injections back in the early 70’s and on a 500 calorie a day diet. This stuff set me up for a lifelong weight problem. You do not need hcg to go on a starvation diet. Anyone that consumes 500 calories a day will loose weight. That is a no brainer folks. The hcg does nothing to make you not hungry you will gain the weight back as soon as you start eating like a normal person again.
Losing weight is changing your lifestyle and 500 calories a day is not a lifestyle change. Out of 5 people in my family that went on this hcg ALL of US have weight issues now. I was 15 years old when I was put on this diet. I needed to lose maybe 15 pounds according to my mother a former model I was grossly overweight.
If you want a lifetime of misery and training your body to go into starvation mode for the rest of your life, go on it. This will be the biggest mistake of your life. I did not think this would ever resurface again, I thought the medical industry would have made more progress in 40 years than reverting back to this. What a shame!!!
Gwen on 13 Jul 2009 at 1:57 pm #
Has anyone actually read the protocol (Cindy)? The diet is much more than hcg and a VLCD. The combinations of foods, the duration of the VLCD and how you reintroduce carbs, starchs and sugar is what makes for success long term.
I for one, have thought the hcg part was nonsense from the beginning but it helped my husband lose 22 pounds on his first round and hopefully another 20 this round. I personally lost 12 pounds and am very close to my ideal weight. I’m not foolish enough to believe that I can lose 10 more and stay healthy and the VLCD is not a long-term diet. How you approach food for the rest of your life is what this diet is all about, not a quick-fix and then back to stuffing yourself.
FYI- we are using an hcg spray (and I wouldn’t be surprised if it was nothing but water!)
Marsha on 17 Aug 2009 at 3:53 am #
My daughter used HCG and has lost 27 pounds and looks great! I was on it for 6 days and the 6th night i woke up 2 or 3 times and it felt like my oxygen was totally cut off—pretty scary!! Hasn’t happened to me before, but don’t know if it was the HCG.I’ve layed around all day not feeling well, so I’ve stopped taking it. Hadn’t lost any weight in the 6 days. But like I said my daughter had great results.May try again later.
mamie on 28 Aug 2009 at 4:34 am #
I’m a first time visitor to the site, just looking for information about this hcg craze. I am really loving the information and its presentation. Finally I feel like I’m getting the kind of unbiased fact-based info I was searching for.
I’ll be back in the future.
Thank you.
ARC on 22 Sep 2009 at 8:03 am #
Cindy!!! thank goodness someone on here has some common sense…people there ARE NO SHORT CUTS! I don’t care how you ‘reintroduce’ food. There is only one rule that applies to weight loss. The law of thermodynamics. if you eat only 500 calories of ding dongs or grapefuit its all the same! a calorie is a calorie…just like a pound of fat is equal to a pound of muscle a pound is a pound. sure from a health perspective it matters but from weight loss it gose like this…
energy in must be less than energy out to lose weight. PERIOD.
even IF hcg helps you feel better when you only eat 500 calories it is setting you up for long term failure…even IF hcg does everything it is purported to do – when you go off the protocol your body will revert and you will gain the weight back. stop paying people to fix your problems. do it yourself. eat right, control your portions and move more. done